تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Dysembryoplastic Neuroepithelial Tumor (DNT): Morphological and Immunohistochemical Features
Dysembryoplastic Neuroepithelial Tumor (DNT): Morphological and Immunohistochemical Features
 
لغة الوثيقة : الانجليزية 
المستخلص : Dysembryoplastic neuroepithelial tumor is a rare mixed neuronalglial tumor. The recognition and correct diagnosis of dysembryoplastic neuroepithelial tumor is important because this tumor is curable by excision. The records of the Pathology Department at King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia, were reviewed for cases that were histologically diagnosed as dysembryoplastic neuroepithelial tumor between 2000 and 2007; five cases were found. The clinical, radiological, histological and immunohistochemical findings were reviewed. The ages ranged between 9 and 25 years. There were 2 males and 3 females. All patients were diagnosed with epilepsy. Three patients had temporal tumor and the other two had frontal tumors. Radiological evaluation showed non-enhancing mass without mass effect or vasogenic edema. All five cases were characteristically composed of small round oligodendroglia-like cells, astrocytes and mature neurones in varying proportions. Immunocytochemistry for glial fibrillary acidic protein and neuronal markers (neuron-specific enolase; and synaptophysin) highlights the astrocytic and neuronal components. The recognition of this tumor is very important because it is a surgically curable lesion with excellent prognosis. Pathologists need to be familiar with the characteristic histopathological findings to avoid unnecessary overtreatment by radiotherapy or chemotherapy. 
ردمد : 0969-711 
اسم الدورية : JKAU: Med. Sci., 
المجلد : 14 
العدد : 3 
سنة النشر : 2007 هـ
2007 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Sunday, April 11, 2010 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
جودة المغربيAl-Maghrabi, Jaudah باحث رئيسيدكتوراه 

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 26399.doc doc 

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